三七中皂苷成分及其药理作用的研究进展.PDFVIP

中草药 Chinese Traditional and Herbal Drugs 第46 卷 第9 期 2015 年5 月 ·1381 · ·综 述· 三七中皂苷成分及其药理作用的研究进展 1, 2 2 2 2, 3 1* 王 莹 ， 扬 ，李 伟 ，马晓慧 ，魏振平 1. 天津大学化工学院，天津 300072 2. 天士力研究院，天士力集团有限公司，天津 300410 3. 天津大学药物科学与技术研究院，天津 300072 摘 要：三七是我国传统中药材，具有抗炎、止血、抗衰老、抗肿瘤等药理活性。三七主要活性成分为皂苷，目前已获取 70 多种皂苷成分。将从三七的不同部位角度，对三七中皂苷成分进行综述。由于大部分皂苷成分均从三七根中获取，而固 液分离法和液液分离法是获取皂苷的传统方法，故将进一步根据获取方法的不同，对三七根中的皂苷成分进行概述。同时将 对三七中皂苷成分药理活性进行简单概述，为三七研究与开发提供有价值的参考。 关键词：三七；三七皂苷；固液分离；液液分离；抗肿瘤 中图分类号：R282.71 文献标志码：A 文章编号：0253 - 2670(2015)09 - 1381 - 12 DOI: 10.7501/j.issn.0253-2670.2015.09.023 Advances in study on saponins in m and their pharmacological activities 1, 2 2 2 2, 3 1 WANG Ying , CHU Yang , LI Wei , MA Xiao-hui , WEI Zhen-ping 1. School of Chemical Engineering and Technology of Tianjin University, Tianjin 300072, China 2. Tasly Academy, Tasly Holding Group Co., Ltd., Tianjin 300410, China 3. School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China Abstract: m , is one of conventional Chinese crude medicine with the pharmacological function of anti-inflammation, hemostasis, anti-aging, anti-tumor, etc. The active constituent is recognized as saponins. To date, more than 70 dammarane-type triterpenoids have been obtained from m . . Since saponins can be obtained from the different parts of mK , according to the different parts, this review summarizes the different saponins. Moreover, saponins are almost obtained from the roots of m . , and liquid-solid isolation and liquid-liquid isolation are the main technologies for obtaining saponins. So by the different technologies, we summarize the saponins obtained from the roots of m . and their pharmacological activ