国产与进口瑞格列奈联合二甲双胍缓释片治疗2型糖尿病的成本-效果分析.docVIP

精品论文 参考文献 国产与进口瑞格列奈联合二甲双胍缓释片治疗2型糖尿病的成本-效果分析 张翠兰 丁 萌 杨立娜 　　（河北涿州市医院内分泌科 河北 涿州 072750） 　　【摘 要】目的：比较国产与进口瑞格列奈联合二甲双胍缓释片治疗2型糖尿病的成本及效果，为临床提供经济有效的治疗方案。方法：选取我院收治的90例2型糖尿病作为研究对象，分为2组，A组46例给予国产瑞格列奈联合二甲双胍缓释片、B组44例给予进口瑞格列奈联合二甲双胍缓释片进行治疗，观察疗效和降糖费用，采用药物经济学中的成本-效果分析法（CEA）进行分析。结果：2组给药方案治疗2型糖尿病的效果相近，但进口药物组使用的费用比国产组明显升高。结论：国产药物组比进口药物组具有较好的成本-效果比，是一种经济有效的2型糖尿病治疗方案。 　　【关键词】2型糖尿病；瑞格列奈,国产与进口；成本-效果分析 　　【中图分类号】R587.1 【文献标识码】B 【文章编号】1003-5028（2015）6-0494-02 　　Cost-effectiveness analysis of domestic vs Imported repaglinide combined with sustained-release tablets of metformin for treating type 2 diabetes mellitus 　　ZHANG Cui-lan，DING Meng，YANG Li-na 　　（Department of Endocrinology ,Zhuo Zhou Hospital，Zhuo Zhou 072750, China） 　　 　　【Abstract】Objective：Comparison of domestic and imported repaglinide combined with sustained-release tablets of metformin in treating type 2 diabetes cost and effectiveness, and to provide a cost-effective treatment options.Methods：Choose 90 patiens with type 2 diabetic patients as the research object，divided into 2 groups, Group A of 46 cases were received domestic repaglinide combined with sustained-release tablets of metformin, Group B (44 cases) were received imported repaglinide treatment combined with sustained-release tablets of metformin, observe the therapeutic effect and glucose-lowering cost ,and use the cost-effectiveness analysis in Pharmacoeconomics (CEA) for analysis. Results：The therapeutic effect are similar between the two groups, but cost of imported drug group was significantly higher than the domestic group. Conclusion：Domestic drug group has better cost-results ratio than imported drug group ,so domestic repaglinide combined with sustained-release tablets of metformin is a economical and effective scheme. 　　【Key words】Type 2 diabetes mellitus; Repaglinide, domestic and imported; Cost-effectiveness analysis 　　糖尿病是一组以高血糖为特征的代谢性疾病群。近年来随着生活水平的提高，人们生活方式的改变及人口老龄化等诸多原因，我国2型糖尿病患病率迅速增加。据2010年发布的流1行病学统计数据，2007年中国成人糖尿病患病率为9.7%［1］。糖尿病及其并发症不仅对患者