活化醇制备羧酸酯.PPT

(3) mostly electron-rich aromatic or heteroaromatic compounds as well as electron-rich alkenes and 1,3-dienes11 are substrates; (4) the transformation is regioselective favoring the less sterically hindered position. 5 Reimer-Tiemann反应 芳香族化合物在碱溶液中与氯仿作用，也能发生芳环氢被甲酰基取代的反应，叫做Reimer-Tiemann反应。 (1) it is the only electrophilic aromatic substitution reaction that occurs under basic conditions in a protic solvent; (2) phenols, naphthols, alkyl-, alkoxy-, and halogenated phenols, salicylic acid derivatives, heterocyclic phenols such as hydroxyquinolin es and hydroxypyrimidines, as well as pyrro