尘肺患者生存质量研究及益气活血化痰中药干预作用.docVIP

精品论文 参考文献 尘肺患者生存质量研究及益气活血化痰中药干预作用 李娜 孙瑞玲 王慧 (山东中医药大学第二附属医院职业病科 山东济南 250001) 【中图分类号】R563 【文献标识码】A【文章编号】1672-5085（2010）34-0011-03 【摘要】目的 观察尘肺患者生存质量研究及益气活血化痰中药的在尘肺治疗中的干预作用。方法 收集62例辩证为气虚血瘀痰阻证的尘肺患者的临床资料，在给予西医常规治疗的基础上加服益气活血化痰中药复方，总疗程为3个月。所有受试者均在治疗前后进行临床症状体征评分、肺功能检查、症状自评量表（SCL-90）评分，综合评估患者的生存质量。结果 治疗1个月后患者咳嗽、咳痰、胸痛及呼吸困难等症状均有所减轻（Plt;0.05），且SCL-90评分中阳性项目数量减少（Plt;0.05）。随着治疗时间延长，临床观察指标继续改善。治疗3个月后，临床主要症状较治疗前相比有显著性差异（Plt;0.01）；SCL-90评分中躯体化、人际关系、抑郁和焦虑因子评分低于治疗前（Plt;0.05），阳性项目数量显著少于治疗前（Plt;0.01）；肺功能检查中用力肺活量占预计值百分比（FVC％）、第1秒用力呼气容积占预计值百分比（FEV1％）较治疗前有所改善（Plt;0.05）。结论 益气活血化痰中药可以减轻尘肺患者临床症状，改善心理状态，保持肺功能的稳定，从而提高尘肺患者生存质量。 【关键词】尘肺病 生存质量 益气活血化痰 SCL-90 肺功能 The Study on the Life Quality of Pneumoconiosis Patients and on the Intervention Effect of Traditional Chinese Medicine on Supplementing Qi, Activating Blood Circulation and Resolving phlegm Li Na ; Sun Rui-ling ; Wang Hui Occupational Disease Department, The Second Hospital Affiliated to Shandong University of TCM 【Abstract】 Objective: To observe the life quality of pneumoconiosis patients and study the intervention effect of traditional Chinese medicine of supplementing qi, activating blood circulation and resolving phlegm in pneumoconiosis treatment. Method: Collect information of 62 cases of pneumoconiosis patients with dialectical qi deficiency, blood stasis and stagnation of phlegm. Treat the patients with Chinese herbal compound of supplementing qi, activating blood circulation and resolving phlegm on the basis of western medicine therapy for a total treatment period of 3 months. Give both pre-treatment and post-treatment score on every subject for his clinical symptoms and signs, pulmonary function test and symptom check list 90, and give comprehensive evaluation of the life quality of the patients. Results: After 1 month of treatment, symptoms of the patients including cough, expectoration, chest pain and dyspnea are all relieved, and the number of positive items in the symptom check list 90 are decreased (Plt;0.05).