左卡尼汀在缺血性心肌病心力衰竭患者中的应用效果评价.docVIP

精品论文 参考文献 左卡尼汀在缺血性心肌病心力衰竭患者中的应用效果评价 侯晶1 闻兴来2 　　(1梅河口市中心医院 135000;2辉南县人民医院 135100) 　　【摘要】目的：探讨在缺血性心肌病心力衰竭患者中对左卡尼汀进行应用的临床效果。方法：对2011～2013年我院收治的64例缺血性心肌病心力衰竭患者进行随机数字表法分组，每组各32例，将其中实施抗血小板聚集、抗心肌缺血、利尿剂及血管紧张素转移酶抑制剂等常规治疗者设为对照组，将在此前提下施加左卡尼汀治疗者设为观察组，评估两组的治疗结局，总结治疗经验。结果：观察组经治疗后，可取得93.8%的临床疗效，较之对照组的68.8%，差异明显（P＜0.05）。治疗后，观察组在左室射血分数（LVEF）、左室舒张末内径（LVEDD）及心输出量（CO）等心脏超声指标方面要较之治疗前、对照组有显著性改善（P＜0.05）。结论：为缺血性心肌病心力衰竭患者提供左卡尼汀进行治疗，能够保障临床疗效，帮助患者改善病情，是今后临床提高本病治疗水平的关键，建议普及。 　　【关键词】左卡尼汀 缺血性心肌病 心力衰竭 应用效果 　　【中图分类号】R453 【文献标识码】A 【文章编号】1672-5085（2014）11-0024-02 　　L-carnitine in patients with ischemic cardiomyopathy heart failure, the application of performance evaluation 　　【Abstract】Objective: to study the in patients with ischemic cardiomyopathy heart failure for application of the clinical effect of l-carnitine. Methods: 2011 cases in our hospital from 2011 to 2013 in patients with ischemic cardiomyopathy heart failure with random number table method group, 32 cases in each group, will be the implementation of anti platelet aggregation, against myocardial ischemia, diuretic and angiotensin transferase inhibitors such as routine treatment as control group, would impose l-carnitine treatment under the premise set as observation group, assess the treatment outcome of the two groups, summarize the treatment experience. Results: the observation group after treatment, the clinical efficacy of 93.8% can be obtained, compared with 68.8% in the control group, significant difference (P lt; 0.05). After treatment, the observation group in the left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDD) and cardiac output (CO), cardiac ultrasound indicators compared with before treatment, control group improved significantly (P lt; 0.05). Conclusion: l-carnitine for patients with ischemic cardiomyopathy heart failure treatment, can guarantee the clinical curative effect, help improve patient, is the key to futur