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- 2018-01-31 发布于上海
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左卡尼汀对婴幼儿病毒性心肌炎CK-MB及 c TnI水平的影响
精品论文 参考文献
左卡尼汀对婴幼儿病毒性心肌炎CK-MB及 c TnI水平的影响
1.鹤岗矿业集团妇幼保健院 黑龙江鹤岗 154100;2.鹤岗矿业集团总医院 黑龙江鹤岗 154100
摘要:目的 探讨左卡尼汀对降低病毒性心肌炎患儿血清CK-MB及cTnI水平的疗效。方法 将60例病毒性心肌炎患儿随机分为两组各30例,治疗组给予左卡尼汀50~100 mg/kg,每日一次静脉滴注;对照组给予辅酶A 100U﹢三磷腺苷40 mg,每日一次静脉滴注,疗程均为14d。采用放射免疫分析法检测患儿治疗前后血清CK-MB及c TnI 水平 结果 治疗组和对照组CK-MB治疗前分别为(52.10plusmn;9.26),(51.94plusmn;10.72)ng /L,治疗后分别为(17.81plusmn;7.76),(25.12plusmn; 7.24)ng/ L(P<0. 01);cTnI 水平治疗前分别为(0.82plusmn;0.19),(0.82plusmn;0.21)U /ml,治疗后分别为(0.18plusmn;0.11),(0.37plusmn;0.12)U /ml(P<0. 01)。结论 左卡尼汀可降低血清 CK-MB、cTnI 水平,对病毒性心肌炎有良好的治疗作用。
关键词:左卡尼汀;CK-MB;cTnI;病毒性心肌炎
Effect of L-carnitine on CK-MB and c TnI levels of infantile virus myocarditis
LI liancui* LI jiabinDelta;
(*Department of Paediatrics,Maternal and Child Health Hospital,Hegang Mining Group,Hegang,Heilongjiang,154100,China;
Delta;Department of Urology,General Hospital of Hegang Mining Group Hegang,Heilongjiang,154100,China;)
【Abstract】 Objective:To evaluate the effect of L-carnitine on reduction serum CK-MB and cTnI levels of viral myocarditis in infantile Methods:60 cases of viral myocarditis were randomly divided into two groups of 30 cases.The treatment group was given L-carnitine 50 ~ 100 mg/kg,once daily intravenous infusion;The control group was given A coenzyme 100U + ATP 40 mg,once daily intravenous infusion,The course of treatment was 14d.Analysis of before and after treatment in children with the method of detection of serum CK-MB and C level of TnI by radioimmunoassayResults:The treatment group and the control group before CK-MB treatment were(52.10 plusmn; 9.26),(51.94 plusmn; 10.72)ng /L,respectively after treatment(17.81 plusmn;7.76),(25.12 plusmn; 7.24)ng/ L(P lt; 0.01);CTnI level before treatment were(0.82 plusmn;0.19),(0.82 plusmn;0.21)U /ml,respectively after treatment(0.18 plusmn;0.11),(0.37 plusmn;0.12)U /ml(P lt; 0.01).
Conclusion:L-carnitine can decrease the serum CK-MB,cTnI levels,has a good therapeutic effect on viral myocarditis.
【Key words】 L-carnitine;C
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