探讨女性甲状腺癌的病理检查结果及预后因素.docVIP

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探讨女性甲状腺癌的病理检查结果及预后因素.doc

探讨女性甲状腺癌的病理检查结果及预后因素

精品论文 参考文献 探讨女性甲状腺癌的病理检查结果及预后因素 大庆油田总医院 163000   摘要:目的 研究并探讨女性甲状腺癌的病理特点以及预后影响因素。方法 此次研究的对象是选取2008年1月—2012年1月,该院收治的女性甲状腺癌患者148例,将其临床资料进行回顾性分析。并对其其临床病理特点以及预后影响因素进行研究。结果 病理检查显示133例(89.9%)甲状腺乳头状癌(PTC),6例(4.1%)为滤泡状癌(FTC),3例(2.0%)为髓样癌(MTC),6例(4.1%)为未分化癌(ATC);病理分期Ⅰ~Ⅱ期占45.3%,Ⅲ~Ⅳ期占54.7%;27例(18.24%)为周围组织侵犯,9例(6.1%)为远处转移,10例(6.76%)对侧甲状腺转移,56例(37.84%)颈部淋巴结转移;1年、3年、5年生存率依次为97.3%、93.2%、83.8%;年龄、病理床分期、病理类型、淋巴结转移、远处转移以及周围组织侵犯均是影响临床预后的重要因素(Plt;0.05)。结论 女性甲状腺癌存在病理分期晚、病理分型差、淋巴结转移、远处转移及局部侵犯率高等不良预后因素,早期影像学检查对临床治疗具有指导意义。   关键词:甲状腺癌;女性患者;病理;临床预后   [Abstract]Objective To study the pathological characteristics and prognostic factors of thyroid carcinoma in female patients.Methods this study was conducted in 148 cases of female patients with thyroid carcinoma in our hospital from January 2012 to January 2008.The clinical data were retrospectively analyzed.And its clinical pathological characteristics and prognostic factors were studied.The results of pathological examination showed that 133 cases(89.9%)of papillary thyroid carcinoma(PTC),6(4.1%)cases of follicular carcinoma(FTC),3 cases(2%)for medullary carcinoma(MTC),6 cases(4.1%)for undifferentiated carcinoma(ATC);pathological stage I-II stage accounted for 45.3% III to IV,accounting for 54.7%;27 cases(18.24%)for the invasion of the surrounding tissue,9 cases(6.1%)for distant metastasis,10 cases(6.76%)metastasis of contralateral thyroid(37.84%),56 cases of cervical lymph node metastasis;1 years,3 years and 5 years survival rates were 97.3%,93.2%,83.8% age,clinical stage,pathology;pathological type,lymph node metastasis,distant metastasis and surrounding tissue invasion are important factors that influence clinical outcome(Plt;0.05).Conclusion the prognosis factors of pathological stage,pathological type,lymph node metastasis,distant metastasis and local invasion rate in female patients with thyroid carcinoma are significant.   Thyroid carcinoma;female patients;Pathology;clinical prognosis   甲状腺癌是临床常见的一种头颈部恶性肿瘤,约占恶性肿瘤总发病率的1%~2%,女性发生率高于男性,男

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