探讨妊娠前体重指数和胎次对妊娠糖尿病合并甲状腺功能减退症发病的影响.docVIP

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探讨妊娠前体重指数和胎次对妊娠糖尿病合并甲状腺功能减退症发病的影响.doc

探讨妊娠前体重指数和胎次对妊娠糖尿病合并甲状腺功能减退症发病的影响

精品论文 参考文献 探讨妊娠前体重指数和胎次对妊娠糖尿病合并甲状腺功能减退症发病的影响 五常市小山子镇卫生院 150211 【摘 要】目的 研究分析妊娠前体重指数和胎次对妊娠糖尿病合并甲状腺功能减退症发病的影响。方法 此次研究的对象是选择2014年8月~2015年12月就诊我院的150例妊娠期妇女,将其临床资料进行回顾性分析,并先按照患者妊娠前的体重指数(BMI)将患者分为体重正常组(52例)、肥胖前期组(47例)以及肥胖组(51例),再按照胎次数将患者分为单胎组(70例)和多胎组(80例)。分别检测记录各组患者的血清游离三碘甲状腺原氨酸(FT3)、血清游离甲状腺素(FT4)和促甲状腺激素(TSH)的水平;统计比较各组妊娠糖尿病合并甲减的发病率;采用非条件Logistic回归模型分析妊娠糖尿病合并甲减的影响因素。结果 肥胖前期组和肥胖组患者血清FT3、FT4的水平较体重正常组明显降???,而TSH的水平明显升高,差异均有统计学意义(P lt; 0.05);体重正常组、肥胖前期组以及肥胖组患者的妊娠糖尿病合并甲减发病率分别为1.9%、3.5%和10.0%,肥胖前期组和肥胖组与体重正常组比较,妊娠糖尿病合并甲减发病率明显升高,差异有统计学意义(P lt; 0.05);单胎组和多胎组患者的妊娠糖尿病合并甲减发病率分别为1.5%和12.0%,多胎组与单胎组比较,妊娠糖尿病合并甲减发病率有明显的升高,差异有统计学意义(P lt; 0.05);非条件Logistic回归分析发现,胎次和BMI都是妊娠糖尿病合并甲减的重要影响因素(回归系数分别为0.854、0.698)。结论 妊娠前BMI和胎次对妊娠糖尿病合并甲减发病的影响重大,有很高的评估价值。 【关键词】妊娠前;体重指数;胎次;妊娠糖尿病合并甲减;影响 [Abstract] Objective To analyze the pregnancy body mass index before and parity on gestational diabetes mellitus complicated with thyroid dysfunction diseases. Methods the study object is 2014 August to December 2015 treatment in our hospital of 150 cases of pregnant women,their clinical data were retrospectively analyzed,and in accordance with the pre pregnancy body mass index(BMI)the patients were divided into the normal weight group(52 cases),pre obese group(47 cases)and obesity group(51 cases),then in accordance with the number of fetal will patients were divided into single pregnancy group(70 cases)and multiple pregnancy group(80 cases). Were used to detect the records in each group of patients with serum free three iodine thyroid original ammonia acid(FT3),free thyroxine(FT4)and promote thyroid hormone(TSH)levels. Statistical comparison of each pregnancy incidence of diabetes complicated with hypothyroidism;using non conditional logistic regression model to analyze the influential factors on the pregnancy diabetes complicated with hypothyroidism. The pre obese group and obese group serum FT3 and FT4 levels compared with normal weight group significantly decreased,while the level of TSH increased significantly,the

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