不同剂量吡嗪酰胺治疗肺结核临床效果观察.docVIP

不同剂量吡嗪酰胺治疗肺结核临床效果观察 黄敬泉 王传香 黄平 江西省赣州市兴国县人民医院感染内科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的:综合分析不同剂量吡嗪酰胺治疗肺结核的临床效果, 为治疗肺结核患者提供科学的数据参考。方法:选取在本院 (2014年12月—2016年12月) 收治的120例肺结核患者, 按照入院顺序随机分为A组 (应用1.5g/d吡嗪酰胺治疗, 40例) 、B组 (应用0.75g/d吡嗪酰胺治疗, 40例) 、C组 (应用0.5g/d吡嗪酰胺治疗, 40例) 。采用SPSS20.0统计学软件进行统计学分析三组患者的临床治疗总有效率、不良反应发生率 (连续治疗一个疗程后出现不良反应) 。结果: (1) C组临床治疗总有效率显著高于A组、B组, 数据比较差异有统计学意义 (P0.05) ; (2) C组不良反应发生率显著低于B组、A组, 数据比较差异有统计学意义 (P0.05) 。结论:应用1.5g/d吡嗪酰胺治疗方法治疗肺结核患者的临床效果最佳。 关键词： 不同剂量; 吡嗪酰胺; 肺结核; 临床效果; 作者简介：黄敬泉, 男, 主治医师, 本科, 主要从事传染病的诊治工作。电话:0797-5317139;E-mail:hj163.com 收稿日期：2017-08-02 Different Doses of Pyrazinamide were used to Observe the Clinical Effect of Tuberculosis HUANG Jing-quan WANG Chuan-xiang HUANG Ping The peoples hospital of Xingguo county, Ganzhou city, Jiangxi province; Abstract： Objective: To comprehensively analyze the clinical effect of different doses of pyrazinamide on tuberculosis and provide scientific data reference for treating pulmonary tuberculosis patients. Methods: 120 cases of pulmonary tuberculosis patients in our college (December 2014-December 2016) were randomly divided into group A (1.5 g/d pyrazinamide treatment method, 40 cases) and group B (0.75 g/d pyrazinamide treatment method, 40 cases) and group C (0.5 g/d pyrazinamide treatment method, 40 cases) . SPSS20.0 statistical software was used to analyze the clinical treatment of three groups of patients with total effective and adverse reaction rate (adverse reactions after a course of treatment) . Results: The total effective rate of clinical treatment in group C was significantly lower than that in group A and group B, and the difference in data was statistically significant (P0.05) . The incidence of adverse reactions in group C was significantly lower than that in group B and group A (P0.05) . Conclusion: 1. 1.5 g/d pyrazinamide is used to treat pulmonary tuberculosis patients with the best clinical effect. Keyword： Different Do