无创正压通气治疗急性左心衰呼吸衰竭43例临床疗效观察.docVIP

精品论文 参考文献 无创正压通气治疗急性左心衰呼吸衰竭43例临床疗效观察 （昆明医学院第五附属医院红河州滇南中心医院呼吸内科 云南 红河 661000） 　　【摘要】 目的：观察无创正压通气治疗急性左心衰的疗效。方法：86例住院急性左心衰患者分为对照组和治疗组,对照组为常规强心、利尿、扩血管治疗；治疗组在此基础上辅以正压通气治疗。观察治疗3天后HR、RR、BP、NT-proBNP、SPO2、PH、PaO2、PaCO2的变化。结果：治疗组患者治疗后HR、RR、SPO2、NT-proBNP、PH、PaO2、PaCO2均较对照组明显改善（Plt;0.05）；对照组与治疗组治疗后血压均无明显变化（Pgt;0.05）。结论：无创正压通气是治疗急性左心衰的一种快速有效的方法。 　　【关键词】 急性左心衰；无创正压通气；呼吸衰竭 　　【中图分类号】R541.6 【文献标识码】A 【文章编号】2095-1752（2016）29-0167-02 　　Clinical efficacy of Non-invasive positive pressure ventilation(NPPV) in treatment of left heart failure with respiratory failure:Report of 43 cases Xu Lin. 　　Fifth Affiliated Hospital of Kunming Medical University/Honghe prefecture central Hospital of southern Yunnan,Gejiu,Yunnan 661000,China 　　【Abstract】Objective To observe the effect of Non- invasive positive pressure ventilation(NPPV) treatment for acute left heart failure with respiratory failure. Methods 86 in-patients with acute left heart failure and respiratory failure were randomly divided into control group and treatment group. Control group had conventionally cardiotonic, diuretic and vasodilator treatment; Treatment group supported by Non-invasive positive pressure ventilation(NPPV) based on the control group. Observe the changes of HR、RR、NT-proBNP、SPO2、PH、PaO2、PaCO2.Results The results of patients in treatment group (HR、RR、NT-proBNP、SPO2、PH、PaO2、PaCO2) had obvious improvement compared with control group (Plt;0.05); There were no changes of blood pressure in both control group and treatment group after treatment (Pgt;0.05).Conclusion Non-invasive positive pressure ventilation(NPPV) is an efficient and effective method to treat acute left heart failure. 　　【Key words】Acute left heart failure; Non-invasive positive pressureventilation(NPPV); Respiratory failure 　　随着临床应用研究的不断深入，无创正压通气已经成为近10余年来临床上常用的辅助通气技术。急性左心衰是临床常见的危急重症之一，以往此类患者出现低氧血症一般不用无创正压通气，近年来观念有所改变。无创双水平气道正压通气（BiPAP）现已越来越多地用于治疗各种呼吸衰竭，包括急性左心衰所致的呼吸衰竭。本文采用BiPAP通气治疗43例急性左心衰低氧血症的患者，取得了良好的临床疗效，现将结果报道