无创正压通气联合呼吸兴奋剂治疗慢阻肺急性加重所致Ⅱ型呼衰患者的疗效随机对照研究.docVIP

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无创正压通气联合呼吸兴奋剂治疗慢阻肺急性加重所致Ⅱ型呼衰患者的疗效随机对照研究.doc

无创正压通气联合呼吸兴奋剂治疗慢阻肺急性加重所致Ⅱ型呼衰患者的疗效随机对照研究

精品论文 参考文献 无创正压通气联合呼吸兴奋剂治疗慢阻肺急性加重所致Ⅱ型呼衰患者的疗效随机对照研究 张国宾1 何燕萍2   (1新疆乌鲁木齐市红十字急救中心 新疆 乌鲁木齐 830000)   (2新疆乌鲁木齐市第一人民医院 新疆 乌鲁木齐 830000)   【摘要】 目的:研究无创正压通气联合呼吸兴奋剂治疗慢阻肺急性加重所致Ⅱ型呼吸衰竭患者的疗效及安全性。方法:选取2013年7月—2014年10月间在我院治疗的120例慢阻肺急性加重合并Ⅱ型呼衰患者作为研究对象,并随机分入观察组和对照组,每组各60例患者。观察组患者采用无创正压通气联合呼吸兴奋剂进行治疗,对照组患者采用有创正压通气进行治疗。结果:两组患者治疗后pH、PaO2、PaCO2较治疗前均明显改善,观察组与对照组组间差异无统计学意义(P>0.05);观察组患者中2例(3.33%)发生并发症或不良反应,对照组患者中10例(16.67%)发生并发症或不良反应,观察组患者并发症和不良反应发生率明显低于对照组,其差异有统计学意义(x2=4.54,P=0.03);观察组患者脱机时间明显短于对照组,其差异有统计学意义(z=-6.40,P=0.00)。结论:应用无创正压通气联合呼吸兴奋剂可以显著改善患者病情,其疗效与有创通气相似,但患者并发症和不良反应发生率更低,脱机时间更短,因此值得在临床推广应用。   【关键词】无创正压通气;呼吸兴奋剂;慢性阻塞性肺疾病;急性Ⅱ型呼吸衰竭   【中图分类号】R563.8 【文献标识码】A 【文章编号】2095-1752(2015)13-0037-02   Study the curative effect of noninvasive positive pressure ventilation in combination with respiratory stimulants for the patients who respiratory failure by caused by copdexacerbations Zhang Guobin. Red Cross Emergency Center of Urumqi, Xinjiang, Urumqi 830000, China; He Yanping. The First Peoples Hospital of Urumqi, Xinjiang, Urumqi 830000, China   【Abstract】Objective Study the curative effect andsafetyof noninvasive positive pressure ventilation in combination with respiratory stimulants for the patients who respiratory failure by caused by copd exacerbations. Methods Selected from July 2013 to October 2014 in our hospital treatment of 120 patients as the research object, randomly divided into observation group and control group, each group of 60 cases. In observation group, treatment by noninvasive positive pressure ventilation in combination with respiratory stimulant .In control group, treated by invasive positive pressure ventilation. Results About complications or adverse reactions, 2 cases in the observation group (3.33%). 10 cases in the control group (16.67%), the difference was statistically significant (P=0.03). Observation group of patients weaning time significantly shorter than the control group, the difference was statistically signifi

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