甲亢性肝病患者血清检验指标改变的临床意义探析.docVIP

精品论文 参考文献 甲亢性肝病患者血清检验指标改变的临床意义探析 周莉 秦建平 肖新华 　　(南华大学第一附属医院 湖南衡阳 421001) 　　【摘要】目的 分析甲亢性肝病患者临床特点。方法 选取于2010年3月到2014年2月住院期间诊断为甲亢的患者190例，其中甲亢性肝病患者40例（研究组），甲亢无肝功能损害150例（对照组）。对比两组间的一般资料、临床表现、血生化指标。结果 甲亢性肝病发病率为21.1%，年龄越大甲亢性肝病发生率越高（P＜0.05）；甲亢性肝病40例中仅5例（13%）出现严重的肝功能损害，其余35例（87%）肝功能损害无症状或轻微不适；研究组ALT、AST、r-GGT、ALP、TT3、TT4均高于对照组（P＜0.05），研究组和对照组间的TSH间差异无统计学意义（P＞0.05）。结论 甲亢患者容易合并肝功能损害，肝损害临床表现多无症状或轻微不适，多发于高龄及病情严重的患者。 　　【关键词】甲亢性肝病 血清指标 临床意义 　　【中图分类号】R446.1 【文献标识码】A 【文章编号】1672-5085（2014）19-0100-02 　　 　　Hyperthyroidism in patients with liver disease analysis the clinical significance of the serum test index change 　　ZHOU Li,QIN Jian-ping,XIAO Xin-hua 　　(The First Affiliated Hospital of Nanhua University,Hengyang,Hunan 421001,China) 　　【Abstract】 Objective To analyze the clinical features of liver disease in patients with hyperthyroidism. Methods for the diagnosis period March 2010 to February 2014 hospitalized patients with hyperthyroidism 190 cases, including 40 patients with hyperthyroidism, liver disease (study group), hyperthyroidism without liver damage 150 cases (control group). General comparison between the two groups, clinical manifestations, blood biochemistry. Hyperthyroidism, liver disease was the result of 21.1%, the older the higher incidence of hyperthyroidism, liver disease (P lt;0.05); hyperthyroidism, liver disease, 40 cases, only five cases (13%) of severe liver damage, and the remaining 35 cases (87%) were asymptomatic or mild hepatic dysfunction discomfort; research group ALT, AST, r-GGT, ALP, TT3, TT4 were higher (P lt;0.05), the difference between TSH between the study group and the control group was not statistically significance (Pgt; 0.05). Conclusion The patients with hyperthyroidism easily combined liver damage, liver damage symptoms or clinical manifestations of mild discomfort, mainly in the elderly and seriously ill patients. 　　【Key words】hyperthyroidism liver disease serum markers Clinical