Research Article The Application of Simple and Easy to….pdfVIP

Hindawi Publishing Corporation International Journal of Spectroscopy Volume 2014, Article ID 289638, 9 pages /10.1155/2014/289638 Research Article The Application of Simple and Easy to Implement Decoupling Pulse Scheme Combinations to Effect Decoupling of Large 戆 Values with Reduced Artifacts Karel D. Klika Molecular Structure Analysis, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69009 Heidelberg, Germany Correspondence should be addressed to Karel D. Klika; klikakd@yahoo.co.uk Received 15 January 2014; Revised 29 March 2014; Accepted 31 March 2014; Published 29 April 2014 Academic Editor: Karol Jackowski Copyright 漏 2014 Karel D. Klika. his is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Of the various problems in decoupling one nucleus type from another using standard decoupling pulse schemes for broadband decoupling, a particular challenge is to efect full, artifact-free decoupling when the size of the coupling constant is very large. Herein it is demonstrated that 1H decoupling of the 31 P NMR spectrum of diethyl phosphonate {HP(=O)(OCH CH ) } can 2 3 2 be accomplished with reduced artifacts despite the large 1戆紿,P value of 693 Hz by using a combination of decoupling pulse schemes involving continuous-wave (CW) irradiation and either adiabatic-pulse decoupling (APD), MPF decoupling, or traditional composite-pulse decoupling (CPD) schemes such as WALTZ or GARP. he considered strategy is simple, eicient, and easy to implement on most instruments. he best