糖化血红蛋白和同型半胱氨酸联合检测在糖尿病微血管病变中的应用.docVIP

精品论文 参考文献 糖化血红蛋白和同型半胱氨酸联合检测在糖尿病微血管病变中的应用 邓喆芳1 邱芬芳1 陈远东2 黄友娜3 　　（1惠州市中心人民医院检验科 516001） 　　（2惠州市第三人民医院检验科 516001） 　　（3惠州市第二妇幼保健院检验科 516001） 　　【摘要】目的 探讨糖化血红蛋白和同型半胱氨酸联合检测在糖尿病微血管病变中的应用价值。方法 选取80例2型糖尿病患者为研究对象，将该组患者按照血糖控制水平及是否合并有微血管病变分为A、B、C三组，A组血糖控制相对稳定未合并有微血管病变；B组血糖控制不佳未合并有微血管病变；C组血糖控制不佳合并有微血管病变。结果 糖尿病组的HbA1c、Hcy、PLT、PDW、MPV均显著高于对照组，有统计学意义(Plt;0.05)。糖尿病C组的HbA1c、Hcy、PLT、PDW、MPV均显著高于A组，有统计学意义(Plt;0.05)。B组的HbA1c、Hcy、PLT、PDW、MPV均显著高于A组，有统计学意义(Plt;0.05)。C组的HbA1c、Hcy、PLT显著高于B组，有统计学意义(Plt;0.05)。结论 HbA1c和Hcy可反映糖尿病微血管病变的严重程度，对糖尿病为血管病变的早期诊断具有重要的检测价值。 　　【关键词】 糖化血红蛋白 同型半胱氨酸 糖尿病 微血管病变 　　【中图分类号】R446 【文献标识码】A 【文章编号】2095-1752（2014）04-0047-02 　　 　　Application of glycosylated hemoglobin and homocysteine detection in diabetic microangiopathy 　　Deng Zhefang 1 Qiu fragrance1 Chen Yuandong 2 Huang Youna 3 　　1、Department of the Central Peoples Hospital of Huizhou 516001 　　2、Laboratory of the third peoples Hospital of Huizhou city 516001 　　3、Department of Huizhou city second 516001 　　【Abstract】 Objective:To explore the application value of homocysteine glycosylated hemoglobin value of combined detection of diabetic microangiopathy.Method:eighty patients with type 2 diabetes for the study,The group of patients according to whether glycemic control and associated with microvascular disease is divided into A, B, C three groups,A relatively stable blood glucose control is not associated with microvascular disease;B group is not associated with poor glycemic control microvascular disease;group C associated with poor glycemic control microangiopathy.Results:In diabetic group of HbA1c 、Hcy、PLT、PDW、MPV were significantly higher, with statistical significance (P lt;0.05).In diabetic group C of HbA1c、Hcy、PLT、PDW、MPV were significantly higher than group A, with statistical significance (P lt;0.05).In group BHbA1c , Hcy, PLT, PDW, MPV were significantly higher than group A, with statistical significance (P lt;0.05).In group