维生素D联合免疫球蛋白治疗对小儿毛细支气管炎患儿机体免疫力的影响.docVIP

精品论文 参考文献 维生素D联合免疫球蛋白治疗对小儿毛细支气管炎患儿机体免疫力的影响 （虞城县人民医院儿科 河南商丘 476300） 　　【摘要】目的：探讨给予小儿毛细支气管炎患儿维生素D联合免疫球蛋白治疗对机体免疫力的影响。方法：选取2013年6月～2015年11月在我院就诊的毛细支气管炎患儿70例，将所有患儿随机分为两组，各35例。对照组进行一般治疗，观察组在对照组基础上给予免疫球蛋白联合维生素D治疗，对比分析两组机体免疫指标及疗效。结果：治疗前后两组的IgM水平对比，无明显差异（P＞0.05）；治疗后对照组的25-（OH）D3、IgA及IgG水平明显低于观察组，差异具有统计学意义（P＜0.05）；观察组的治疗总有效率为97.1%，明显高于对照组的68.6%，差异具有统计学意义（P＜0.05）。结论：给予小儿毛细支气管炎维生素D联合免疫球蛋白治疗的临床疗效较好，可明显提高患儿的机体免疫能力，改善临床症状，利于预后，减少并发症的发生，缩短患儿的康复时间。 　　【关键词】维生素D；免疫球蛋白；小儿毛细支气管炎；机体免疫力 　　【中图分类号】R720.5 【文献标识码】A 【文章编号】1007-8231（2016）18-0030-02 　　 Effect of vitamin D combined with immunoglobulin therapy on immune function in children with bronchiolitis 　　 Xue Ying.Department of Pediatrics, Yucheng Peoples Hospital, Yucheng Henan 476300 　　【Abstract】Objective To investigate the effect of vitamin D combined with immunoglobulin therapy on immune function in children with bronchiolitis. Methods 70 cases of children with bronchiolitis in our hospital from June 2013 to November were randomly divided into two groups, each of 35 cases. The control group was treated with general treatment, the observation group was given the immune globulin combined with vitamin D treatment on the basis of the control group. The two groups were compared and analyzed. Results Before and after treatment in two groups of IgM levels were compared, no significant difference (Pgt;0.05); after treatment in the control group, 25 (OH) D3, IgA and IgG levels was significantly lower than that of the observation group, the difference has statistical significance (Plt;0.05); treatment observation group, the total effective rate was 97.1%, significantly higher than the 68.6% of controls, the difference has statistical significance (Plt;0.05). Conclusion Children with capillary bronchitis vitamin D combined with immune globulin therapy clinical curative effect is good, can significantly improve the immune ability of children, improve the clinical symptoms, beneficial to the prognosis, reduce c