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一种治疗顽固性高血压的新方法:经导管肾神经消融;Background
? Hypertension is a global public health problem of major magnitude
? An estimated 30-40% of the adult population in the developed
world suffers from this condition.
? Despite numerous safe and effective pharmacological therapies,
only~50% of patients achieve blood pressure control to guideline
targets
? Renal sympathetic efferent and afferent nerves, which lie in the
wall of the renal artery, have been recognized as seminal in the
initiation and maintenance of systemic hypertension;Catheter-based renal sympathetic denervation for resistant hypertension:
a multicentre safety and proof-of-principle cohort study.
Lancet 2009; 373: 1275– ;More information; Symplicity HTN-2: Denervation effective for treating resistant hypertension Lancet 2010; Advance online A group of 100 patients who, despite taking three or more antihypertensive drugs, had a baseline systolic BP of ≥160 mm Hg – ≥150 mm Hg for type 2 diabetics – were randomly assigned to ;Novel therapeutic targets for hypertension Ludovit Paulis, Thomas Unger Nature Reviews Cardiology 7, 431-441 (August 2010) ? ;Thanks Thanks Thanks Thanks Thanks Thanks
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