LocalAnesthetics局麻药.pptVIP

Local Anesthetics Liming Zhou (周黎明） Department of pharmacology Contents Introduction and history Mechanisms of action Pharmacokinetics Pharmacological effects Clinic use Adverse effects Common drugs Introduction history Cocaine is a naturally occurring compound It was the first anesthetic to be discovered and is the only naturally occurring local anesthetic Introduction history many of cocaines pharmacologic actions and adverse effects were elucidated in the latter half of the 1800s. Koller introduced cocaine to the field of ophthalmology. Hall introduced it to