银川干细胞20170706PPT.ppt

会议内容 青年论坛 开幕式、大会报告 分会场（1/2/3）报告 分会场（4/5/6）报告 CMV-specific T cell transfer promotes the quantitative and qualitive immune recovery for refractory CMV infection after haploidentical stem cell transplantation（Peking University People’s Hospital） Background: Cytomegalovirus (CMV) infection is a major cause of morbidity and mortality in allogeneic stem cell transplant (allo-SCT) recipients，particularly in those patients who undergo haploidentical stem cell transplantation (haplo-SCT). Adoptive immunotherapies with CMV-specific T cells have been developed for the treatment of CMV infection，and several clinical trials have established the safety and efficacy of adoptive T cells for prophylaxis and treatment of CMV infection. However，few experiences have been reported about CMV-specific T cells in adoptive therapy post haplo-SCT. Methods: A total of 32 patients with refractory CMV infection prospectively accepted adoptive CMV-specific T cells infusion following haplo-SCT were enrolled. Another group of 32 patients with non-refractory CMV infection after haplo-SCT was selected as controls. We analyzed the phenotypical and functional characteristics of CMV-specific T cells and their subsets before and after immunotherapy in the refractory CMV cohort， and also in the non-refractory CMV cohort. We aimed to(i) evaluate the safety and antiviral activity of CMV-specific T cells for refractory CMV infection in haplo-SCT recipients. 18 cases In 83% of cases CMV infection was cleared or viral burden was significantly reduced Viral control was associated with in vivo expansion of CMV-specific T cells 异体干细胞治疗牙周炎的基础及转化临床研究王松灵首都医科大学 在大型动物模型-小型猪上建立了牙周炎模型。用自体、异体牙源干细胞成功修复牙周炎致牙周骨缺损。 牙源性干细胞再生牙周的效果比非牙源性干细胞好；牙髓干细胞保持细胞的干性及抗凋亡衰老能力明显优于其他干细胞。牙髓干细胞悬液注射组可以用于相对轻型的牙周病组织再生。18例异体牙髓干细胞治疗慢性牙周炎临床研究表明有明显牙周组织再生，无副作用。 通过建立牙源干细胞库、牙髓干细胞注射液新药应用到临床 人牙髓间充质干细胞注射液 自体干细胞技术的临床应用肖海蓉??石桂来博雅干细胞科技有限公司 博雅集团旗下 Cesca 公司(纳斯达克上市企业)是全球领先的干细胞自动化设备供应商，拥有全球市场占有率超过 60%的脐带血干细胞自动化分离设备(AutoXpress?)及全球唯一的自动化液氮存储装置(B