2009年最新进展：Updated and new commands for meta-analysis in Stata.pdfVIP

Updated and new commands for meta-analysis in Stata™ Michael J. Bradburn Cancer Research UK Medical Statistics Group, Centre for Statistics in Medicine, Oxford, UK This document and the Stata programs referred to build on previous work done in collaboration with Jon Deeks and Doug Altman from the Centre for Statistics in Medicine, Oxford. The dialog box interface was written by Tom Steichen. 1 Introduction Meta-analysis is the statistical methodology used to combine data from two or more studies that have addressed the same question. Several methods for this type of analysis have been implemented in the Stata software, including basic analyses of aggregate data (meta and metan commands), cumulative meta-analysis (metacum), diagnostics (metainf, metabias, metatrim, galbr, funnel) and meta-regression (metareg). All of these programs were originally written for the Stata Technical Bulletin, and are described in detail in the respective submissions. Chapter 18 of Egger et al. (2001; available online at /books/sysrev/chapter18.pdf) forms a more complete introduction to meta-analysis in Stata. This text describes only a subset of these methods. The article falls in two parts: to illustrate enhancements to the metan, funnel and labbe programs previously submitted to the Stata Technical Bulletin in 1998 (Bradburn et al.), and to introduce a new command, metannt. Section 2 starts by recapping on what the existing programs do before summarising the new additions, together with examples that demonstrate their use, and will also introduce the new dialog box interface. In section 3, the new routine will be introduced and demonstrated, and some final remarks made in section 4. A full list of options available for all four the programs is given in the appendix. 2. The metan, funnel and labbe commands 2.1 Aggregate data meta-analysis (metan) 2.11 Present capabilities The original 1998 version of metan combines 2x2 tables or