琥珀酸脱氢酶抑制剂类杀菌剂的研发进展_仇是胜.pdfVIP

第13 卷 第6 期 现 代 农 药 Vol.13 No.6 2014 年12 月 Modern Agrochemicals Dec. 2014 琥珀酸脱氢酶抑制剂类杀菌剂的研发进展 ( Ⅰ) 1 2 仇是胜 ，柏亚罗 （1. 江苏嘉隆化工有限公司，江苏徐州 221112 ；2. 江苏省农药研究所股份有限公司，南京 210024 ） 摘要：琥珀酸脱氢酶抑制剂类 (SDHI) 杀菌剂历经3 代，有 18 个品种上市或即将上市。尤其 是第3 代8 个吡唑酰胺类杀菌剂的问世，有力地带动了SDHI 类杀菌剂市场的迅速发展。介绍了 SDHI 类杀菌剂的作用机理、构效关系和专利概况，逐个陈述了它们的应用与市场，总结了该类 产品的抗性情况及产生机理，并展望了SDHI 类杀菌剂的发展前景。 关键词：琥珀酸脱氢酶抑制剂；酰胺类杀菌剂；研究开发；应用；市场；抗性 中图分类号：TQ 455.4＋9 文献标识码：A doi ：10.3969/j.issn.1671-5284.2014.06.001 Progress on Research and Development of Succinate Dehydrogenase Inhibitor Fungicides ( Ⅰ) 1 2 QIU Shi-sheng , BAI Ya-luo (1. Jiangsu Jialong Chemical Industry Co., Ltd., Jiangsu Xuzhou 221112, China; 2. Jiangsu Pesticide Research Institute Co., Ltd., Nanjing 210024, China) Abstract: Eighteen fungicides of succinate dehydrogenase inhibitors (SDHI) have launched or will launch soon through three-generation-development. Especially, the sales of eight carboxamide fungicides in the 3rd generation, promoted significantly the market development of SDHIs. The paper introduced the mechanism of action, structure- activity relationships and patent profiles of SDHIs. The uses and markets of the all active ingredients were described, their resistance and resistant mechanisms were summaried, and the futures of SDHIs were also prospected. Key words: succinate dehydrogenase inhibitor (SDHI); carboxamide fungicide; RD; use; market; resistance 转基因作物发展迅速，在挤压了除草剂和杀虫 用机理给这类产品单独归类，它们因作用于病原菌线 剂市场的同时，为杀菌剂营造了相对宽松的环境。