响应面分析法优化当归多糖提取工艺-连云港中医药高等职业技术学校.PDFVIP

146 2012, Vol. 33, No. 10 食品科学 ※工艺技术 响应面分析法优化当归多糖提取工艺 1 2 , 3 王艳艳 ，王团结 * ，丁琳琳 ( 1.江苏联合职业技术学院连云港中医药分院，江苏连云港 222006 ； 2 .江苏康缘药业股份有限公司，江苏连云港 22200 1；3.天津红日药业股份有限公司，天津 30 1700) 摘 要：目的：优选当归多糖的提取工艺。方法：以当归多糖为评价指标，通过响应面分析法优化当归多糖的 提取工艺，并对最佳提取工艺进行验证实验。结果：当归多糖的最佳提取工艺为每次提取时间2 . 15h 、料液比 1:8 .2 7(g/mL ) 、提取3 次。结论：采用响应面分析法优化对当归多糖提取条件进行优化合理可行。 关键词：响应面；当归；多糖；提取工艺 Optimization of Polysaccharide Extraction from Angelica sinensis Using Response Surface Methodology 1 2, 3 WANG Yan-yan ，WANG Tuan-j ie * ，DING Lin-lin (1. Lianyungang Branch of Traditional Chinese Medicine, Jiangsu Union Technical Institute, Lianyungang 222006, China ； 2. Jiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang 22200 1, China； 3. Tianj in Chasesun Pharmaceutical Co. Ltd., Tianj in 30 1700, China) Abstract ：Obj ective: To research the optimal extraction conditions of polysaccharide from A ng elica sinensis . Methods: Response surface methodology (RSM) was applied to optimize the best extraction conditions, and then verified the optimal conditions. Results: The optimal conditions were as follows: the time for 2.15 h, solid-liquid ratio at 1:8.27, and extraction times for 3 times. Conclusion : It is feasible to optimize the extraction processing of polysaccharide from Ang elica sinensis by RSM. Key words ：respon se surface methodology ；A ng elica sinensis ；poly saccharide ；extraction 中图分类号：R284 .2 文献标识码：A 文章编号：1002-6630(20 12) 10-0 146-04 当归为伞形科植物当归[Angelica sinensis (Oliv.) Diels] 1.1 材料、试剂与仪器 的干燥根，