谷氨酰胺应用于重症急性胰腺炎病人肠内营养的临床观察.docVIP

不同时期肠内应用谷氨酰胺对SAP患者临床效果的比较 李慎美，郝春艳 辽宁医学院，121001 【摘要】：目的 观察重症急性胰腺炎病人在不同时机应用谷氨酰胺进行肠内营养后的临床治疗效果。方法 选择60例重症急性胰腺炎患者分成3组，每组20例，分别在第1天、第3天、第7天开始应用谷氨酰胺进行肠内营养治疗，记录相应的营养指标、免疫指标、胰腺恢复情况，最后对实验结果进行统计学处理。 结果 血清白蛋白和前白蛋白检测：第1组第2组第3组，且组间差异均有统计学意义（P0.05）；IgG、IgA、IgM检测均为第1组第2组第3组，且组间差异均有统计学意义（P0.05）；C反应蛋白检测：第1组第2组第3组，且组间差异均有统计学意义（P0.05）；APACHEII评分情况：第1组第2组第3组，且组间差异均有统计学意义（P0.05）；结论 重症急性胰腺炎患者肠内营养应用谷氨酰胺的时机越早越好。 【关键词】 重症急性胰腺炎；肠内营养；谷氨酰胺；疗效 To Study the diffrent Timing of Glutamine Using by Enteral Nutrtion to the Patients with Severe Acute Pancreatitis/LiaoNing Mediacal University(LI Shen-mei), First Affiliated Hospital of Liaoning Medical University(HAO Chun-yan)//LiaoNing JinZhou, 121001 【abstract】：Objective To observe the effect of different?timing of?the glutamine（Glu）?by?enteral nutrition to the patients with svere acute pancreatitis（SAP） . Methods The 60 severe acute pancrititis were divided into three groups. Evrery groupe have twenty cases, and the application of Glu to the patients in the 1st day ,the 3rd day, the 7th day espectlvely, and then observe and record the nutrition indicators,the immunological parameters,the number of days staying in intensive care unite ( ICU), the infections indicators of the three groups , for statistical analysisi. Results After the experiment,?the serum albumin?and?prealbumin?level are increased higher?in group1?than?group 2 higer than?group 3,?and? the difference has statistical significant (P 0.05);IgG, IgA, IgM were higher in group 1than group 2 higher than group 3, the difference has statistical significant (P0.05); the C-reactive protein?in group 1 are lower than?group2 lower than?group 3,?and the difference has statistical significant (P0.05); Acute Physiology and Chronic Health Evaluation (APACHEII?score)?in group 1 are lower ?than?group 2 lower than?group 3, and the difference has statistical significant (P0.05);?Conclusions The timing of the effect of gutamine application through the enteral nutrition support to the patients with sev