季松血管内介入栓塞治疗后交通动脉瘤伴动眼神经麻痹对疗效及神经功能的影响.doc

血管内介入栓塞治疗后交通动脉瘤伴动眼神经麻痹对疗效及神经功能的影响 【摘要】目的：分析血管内介入栓塞治疗后交通动脉瘤伴动眼神经麻痹对疗效及神经功能的影响。方法：回顾性分析2013年1月-2014年12月本院诊治的86例后交通动脉瘤伴动眼神经麻痹患者临床资料，按照不同手术治疗方式分为两组（各43例），对照组行显微外科手术治疗，研究组行血管内介入栓塞治疗，对比两组临床具体治疗情况。结果：研究组手术时间、拔除导管时间均比对照组短，并且术中出血量低于对照组（P＜0.01）；研究组NSE、IUPAC及Glucose指标水平均显著低于对照组（P＜0.05）；两组动眼神经恢复总有效率相当（P＞0.05）；研究组脱水、血管痉挛及脑水肿发生率比对照组低（P＜0.01，P＜0.05）。结论：血管内介入栓塞治疗后交通动脉瘤伴动眼神经麻痹疗效良好，可以有效改善患者神经功能，同时能够降低并发症发生率。 【关键词】血管内介入栓塞;显微外科手术;后交通动脉瘤;动眼神经麻痹 Study on the Curative Effect of Interventional Endovascular Embolization for the Treatment of Posterior Communicating Aneurysm Plus Oculomotor Nerve Palsy and its Effect on Patients’ Nerve Function [Abstract] Objective: To analyze the clinical effect of interventional endovascular embolization for the treatment of posterior communicating aneurysms with oculomotor nerve palsy as well as its effect on patients’ nerve function. Methods: The clinical data of 86 patients treated in our hospital for posterior communicating aneurysm plus oculomotor nerve palsy between January 2013 and December 2014 were reviewed, and according to the different operations adopted, the patients were divided into two groups (each with 43 cases), where the control group underwent microsurgical operation for treatment yet the study group underwent interventional endovascular embolization. The relevant clinical items of treatment were compared between the two groups. Results: The operation duration and time consumed for the removal of catheter in the study group were shorter than the control group, and its blood loss during the operation was lower than the control group (P0.01). Such indexes as NSE, IUPAC and Glucose of the study group were significantly lower than those of the control group (P0.05). However, there was no significant difference in total efficiency of recovery of oculomotor nerve between the two groups (P0.05). The incidence of dehydration, vasospasm and brain edema in the study group was lower than the control group (P0.01, P0.05). Conclusion: Interventional