日本普通人群中代谢综合征及植物甾酮的吸收异常发生率演示课件.pptVIP

The 4th Shino-Japan Cardiovascular Forum on October 23-24, 2008 in Beijing Frequency of Metabolic Syndrome and its Absorption Abnormality by Plant Sterols in General Population, Japan Toshio Shimada, Yo Murakami, Nobuyuki Oyake, Hiroyuki Yoshitomi, Nobuhiro Kodani, Akira Matsumori* Division of Cardiovascular Medicine, Department of Internal Medicine, Shimane University Faculty of Medicine, Department of Cardiovascular Medicine, Kyoto University, Graduate School of Medicine* Background Health problems on aged people have been growing bigger in Japan because with advancing age, a variety of diseases especially on vascular diseases, such as cardio- and cerebro-vascular diseases have been increasing. And therefore, early detection of vascular diseases is a very important issue for vascular prevention and reduction of mortality.　 Diagnostic Criteria for Metabolic Syndrome (8 Japanese Medical Associations Joint-Committee) Fat accumulation in the intra-abdominal cavity 　　Abdominal Circumference at the Waist　Male≧85cm, Female≧90cm(≧ 80cm recommended by me) 　　（Visceral fat area　Male and Female ≧100 cm2) 　Hypertriglyceridemia　 　　≧150 mg/dL 　Low HDL-cho　　 ＜40 mg/dL 　Systolic Blood Pressure　　　 ≧130 mmHg 　Diastolic Blood Pressure　　　 ≧ 85 mmHg 　Fasting Blood Sugar　　 ≧110 mg/dL ? Lipoprotein abnormality ? High Blood Pressure ? High Blood Sugar ＋ At least, more than following 2 items and / or and / or modified and translated into English by Toshio Shimada ?Major Criteria ?Minor Criteria Obesity Insulin Resistance DM Dyslipidemia Hypertension Atherosclerosis Arteriosclerosis Pathophysiology of Metabolic Syndrme Over-eating Poor Exercise Inheritance LDL レ セ プ タ I Synthesis of Cholesterol in the Liver and Absorption of Cholesterol in the Intestine- Two Important Supply Sources of Cholesterol in Vivo- Bile Food Liver Vessels Cholesterol Small Intestine Biliary 800~2000mg/day Dietary 400~500mg/day Aim Our purpose is to investigate the frequency of metabolic syndrome (MS) and li