结直肠癌肝转移新辅助化疗的共识与争议演示幻灯片.pptVIP

Clinical outcome related to liver damage Steatosis associated with higher infection rate (Kooby et al, 2003) Steatohepatitis associated with higher mortality rate due to liver failure after surgery (Vauthey et al. 2006) Vascular injury associated with higher rate of operative bleeding and transfusion requirement (Vauthey et al. 2006. Aloia et al. 2006 ) Peroperative chemotherapy:potential problems EORTC 40983:impact of pre-operative chemotherapy on surgery B O S (Biologics,Oxaliplatin,Surgery)EORTC 40051 Resectable CRC liver metastases: Unanswered Questions Is peri-operative