Epoxide Formation from Diallyl Sulfone Is Associated with…二烯丙基砜形成的环氧化物与相关.pdfVIP

Epoxide Formation from Diallyl Sulfone Is Associated with CYP2E1 Inactivation in Murine and Human Lungs Poh-Gek Forkert, Peter D. Premdas, and Raymond J. Bowers Departments of Anatomy and Cell Biology and Chemistry, Queen’s University, Kingston, Ontario, Canada We tested the hypothesis that an epoxide formed from diallyl ethylene (DCE), a compound that is used in the manufac- sulfone (DASO ) is responsible for inactivation of CYP2E1 in mu- 2 ture of plastics and that is a prevalent water con