Transmembrane protein polymorphisms and resistance to T …跨膜蛋白多态性和对的耐药性.pdfVIP

Virus Genes (2007) 35:167–174 DOI 10.1007/s11262-007-0098-8 Transmembrane protein polymorphisms and resistance to T-20 (Enfuvirtide, Fuzeon) in HIV-1 infected therapy-naive seroconverters and AIDS patients under HAART-T-20 therapy Vladimir A. Morozov Æ Alexei V. Morozov Æ ¨ ¨ Dirck Schurmann Æ Heiko Jessen Æ Claudia Kucherer Received: 29 December 2006 / Accepted: 16 March 2007 / Published online: 18 April 2007 Springer Science+Business Media, LLC 2007 Abstract The human immunodeficiency virus type 1 v