【体外膜肺ECMO精品课件】 Hypoxaemia.ppt

HypoxaemiaWhat is the limit?;To begin with….;What is normal arterial oxygenation?;What is normal arterial oxygenation?;Compensatory mechanism?;What is normal arterial oxygenation?;Lower limit;Experience in children with cyanotic heart disease;At the end of a normal inspiration, AMREE team members would expire quickly and deeply through the mouthpiece and hold their breath for a second or so at residual volume. By pulling a lever on the alveolar gas sampler, the valve on the small pre-evacuated aluminum canister would open. Once the sample was collected, the valve could be closed by releasing the lever.;Who is this Guy ?;Pulmonary gas exchange on the summit of Mount Everest;Alveolar gas and estimated arterial blood values on the summit of Mt Everest (8848 m);Caudwell Xtreme Everest 2007;Caudwell Xtreme Everest 2007;;Caudwell Xtreme Everest;Caudwell Xtreme Everest;Base Camp(5300);Exercise test at Base Camp (5,300m);Camp 2 – Erecting Drash Lab;Arterial blood sampling;South Col Lab ( 8000m);Challenging the height – Mt Everest;Death Zone;Summit;Summit;Blood Gas at 8400m;Arterial blood gas in the death zone;What can we learn?;Physiology of hypoxaemia;Hypoxia inducible factors ( HIF);;Physiology of hypoxaemia;What is the implication to daily clinical practice?;What is the implication to daily clinical practice?;A patient with severe hypoxaemia;A patient with severe hypoxaemia;A patient with severe hypoxaemia;A patient with severe hypoxaemia;A patient with severe hypoxaemia;;A patient with severe hypoxaemia;;;A patient with severe hypoxaemia;;A patient with severe hypoxaemia;A patient with severe hypoxaemia;A patient with severe hypoxaemia;A patient with severe hypoxaemia;Conclusions: