非beta-内酰胺类抗生素(英文课件)Nonbeta-lactam antibiotics.pptVIP

Assoc. Prof. Ivan Lambev e-mail: itlambev@mail.bg;β-lactams Glycopeptides;Aminoglycosides have a hexose ring, either streptidine (in streptomycin) or 2-deoxystreptamine (other aminoglycosides), to which various amino sugars are attached by glycosidic linkages. They are water-soluble, stable in solution, and more active at alkaline than at acid pH.;Streptomycin;Streptomycin is an aminoglycoside antibiotic. Its antibacterial activity is due to it binding to the 30S subunit of the bacterial ribosome and inhibiting of protein synthesis. It has a wide spectrum of anti- bacterial activity but is