抗生素的选择(英文)ANTIBIOTICS - ASHWINI.pptVIP

ANTIBIOTICS;The selection of antibiotic therapy for an infection requires a knowledge of: 1The infecting organism, including the pathogen most likely to be present in given clinical or geographical circumstances 2The local patterns of antimicrobial resistance in common pathogens 3 An understanding of the pharmacokinetics of the antimicrobials selected 4 The physiology of the patient, metabolic upset, renal or hepatic dysfunction, age and available routes of administration. The clinical history should determine the systems of the body most likely to be involved in disease. Figure 6.3 (p. 1