抗生素耐药与新型抗生素Bacterial Pathogens in the Hospital and Community- The Need for Newer Antibiotics.pptVIP

Bacterial Pathogens in the Hospital and Community: The Need for Newer Antibiotics ?;So What Happened?;So What Happened?;Tennessee;Bad Bugs, No Drugs1;Between 1962 and 2000, no major classes of antibiotics were introduced ;;Enterobacteriaceae;Copyright restrictions may apply.;Increase in numbers of Group 1, 2 and 3 β-lactamases from 1970 to 2009;Bush K and Jacboy G AAC 2010;Extended-Spectrum β-Lactamases;;CTX-M-type ESBLs ;Carbapenemases;KPC (K. pneumoniae carbapenemase);Nordmann P et al. LID 2009;Bush K and Jacboy G AAC 2010;AmpC β-lactamases;;Enterobacteriaceae: Breakpoints revised;Neisseria