Sequence Alignment
北京大学生物信息学中心高歌
Ge Gao, Ph.D.
Center for Bioinformatics, Peking University
Unit 2:
Global Alignment
by Dynamic Programming
北京大学生物信息学中心高歌
Ge Gao, Ph.D.
Center for Bioinformatics, Peking University
Pairwise Sequence Alignment: in Maths
• Input data:
– Two sequences S1 and S2
• Parameter(s)
– A scoring function f for
• Substitutions
• Gaps
• Output:
– The optimal alignment of S1 and S2, whi
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