(精编)【高血压英文教学精品课件】 Blood Vessels.pptVIP

Blood Vessels Frank A. Acevedo, PA-C Vascular Abnormalities Narrowing of the lumen Thrombosis Weakening of the walls Normal Intima - Endothelial Cells Media - Smooth Muscle Cells Adventitia - Connective Tissue Arteries Elastic arteries Muscular arteries Arterioles Congenital Anomalies Berry aneurysms AV fistulas Atherosclerosis Elastic and medium sized arteries Atheroma is the basic lesion Age, male, genetic LDL, VLDL Monocytes - macrophages - foam cells Endothelial injury Atherosclerosis Atherosclerosis Atherosclerosis Atherosclerosis Risk Factors Major diet and hyperlipidemia, hypertension, cigarette smoking, diabetes Minor obesity, lack of exercise, age, male, family history, stress, BCP, High CHO intake, hyperhomocysteinemia Hypertension Idiopathic, essential Renin - Angiotensin Accelerated atherogenesis Hyaline atherosclerosis Vasculitides Giant cell arteritis Takayasu’s arteritis Polyarteritis nodosa Kawasaki disease Wegener’s granulomatosis Buerger’s disease Giant Cell Arteritis Rare before age 50 Throbbing pain Visual disturbances Temporal artery Corticosteroids Polymyalgia rheumatica Giant Cell Arteritis Giant Cell Arteritis Takayasu’s Arteritis Fibrous thickening of aortic arch Upper extremity pulselessness Females 15 - 40 Polyarteritis Nodosa Systemic involvement Fever, weight loss, hypertension Abdominal pain Melena Muscle aches Motor peripheral neuropathy Polyarteritis Nodosa Kawasaki Syndrome Young children and infants Fever, conjunctival and oral erythema and erosion, edema of the hands and feet, erythema of the palms and soles, desquamation, lymph node enlargement Leading cause of acquired heart disease in children Wegener’s Granulomatosis Acute necrotizing granulomas of the upper and lower reap tract Focal necrotizing vasculitis Renal disease 5th decade of life Immunosuppressive therapy Wegener’s Granulomatosis Buerger’s Disease Thromboangitis obliterans Cigarette smoking “instep” claudication Buerger’s Disease Buerger’s Disease