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References(continued) Ries LAG, Eisner MP, Kosary CL, Hankey BF, Miller BA, Clegg L, Mariotto A, Fay MP, Feuer EJ, Edwards BK (eds). SEER Cancer Statistics Review, 1975-2000, National Cancer Institute. Bethesda, MD, /csr/1975_2000/,2003. U.S. Renal Data System, USRDS 2004 Annual Data Report: Atlas of End-Stage Renal Disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2004. U.S. Renal Data System, USRDS 2003 Annual Data Report: Atlas of End-Stage Renal Disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2003. U.S. Renal Data System, USRDS 2000 Annual Data Report: Atlas of End-Stage Renal Disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2000. Rates of ESRD have been almost doubling each decade. This slide compares ESRD to the 4 most serious cancers. While there is no intention to imply that one disease is worse than another, many people are not aware how the incidence of ESRD ranks. We know that people with ESRD can be sustained with transplants or dialysis. However, the mortality after ESRD is reached, particularly on dialysis, is so high (about 20% per year), that as many people die while being treated for uremia as from any cancer except lung cancer. The pool of chronic kidney disease from which the cases of ESRD develop is very large. These data from the National Health and Nutrition Examination Survey (NHANES) indicate that about 19-20 million Americans have substantially depressed GFR and/or persistent microalbuminuria or even greater albuminuria. Diabetes is the most rapidly rising cause of ESRD, but the hypertension rate also continues to rise. This map shows the incidence rates for ESRD in 1990 with the highest rates in the Southeast. This map from 10 years later shows that rates have
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