(精编)【高血压英文教学精品课件】 HYPERTENSION DIABETES “A DANGEROUS DUO”.pptVIP

The presence of diabetes further increases the already elevated risk associated with hypertension. The higher the systolic blood pressure (SBP), the greater the absolute excess risk for cardiovascular (CV) mortality among diabetic patients. In the large cohort of men screened for MRFIT (the Multiple Risk Factor Intervention Trial), the relationship of SBP and other CV risk factors to CV mortality was compared in men with diabetes (n=5163) and in men without diabetes (n=342,815). The absolute risk of CV death was 3 times higher for men with diabetes than for men without diabetes after adjusting for age, race, income, serum cholesterol, SBP, and cigarette smoking (P0.0001). SBP had a positive relationship with the risk of CV death, with a significant trend in subjects with or without diabetes (P0.001). At every SBP level, CV death was much greater for men with diabetes than for men without diabetes. With higher SBP levels, the CV mortality rate increased more steeply in men with diabetes than in men without diabetes. The combination of diabetes and hypertension thus dramatically increases CV risk. References Stamler J, Vaccaro O, Neaton JD, et al. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care. 1993;16:434-444. Metabolic Syndrome: A Constellation of Risk Factors and a Cause for Concern Metabolic syndrome is “a constellation of lipid and nonlipid risk factors of metabolic origin.” According to the National Cholesterol Education Program/Adult Treatment Panel III, metabolic syndrome is diagnosed by the presence of at least 3 of 5 risk factors, as follows1: Abdominal obesity Elevated blood pressure Elevated fasting glucose Elevated triglycerides Low high-density lipoprotein cholesterol (HDL-C) The relationship between metabolic syndrome and obesity is the focus of this slide presentation, which will demonstrate how the management of obesity to achieve a modest we