(精编)Diagnostic and Therapeutic Potential of Small Nucleic Acid Molecules教学课件.pptVIP

Reactive GC in a hyperplastic tonsil PRDM1-negative HRS cells Weakly positive HRS cells IRF4/MUM1 positive PRDM1 Immunohistochemistry (HL Cases) Nie, K. et al, Am J Pathol 2008, 173:242-252, Figure 5D Transfection of mir-9 or let-7a Alters Endogenous PRDM1 Expression Nie, K. et al, Am J Pathol 2008, 173:242-252 Figure 6A Nie, K. et al, Am J Pathol 2008, 173:242-252 Figure 6B Transfection with anti-micro RNA Increases PRDM1 Protein Levels Hypothetical Model of microRNA-mediated PRDM1 Inactivation in Pathogenesis of Hodgkin/Reed-Sternberg Cells: PRDM1 protein levels do not accumulate despit