(精编)Identification of microRNA function by target prediction and expression profiling教学课件.pptVIP

Youngae Lee Identification of microRNA function by target prediction and expression profiling MicroRNA (miRNA) ? A new family of small noncoding RNA (~22 nt) ? ~250 miRNA in animal ? Inhibition of translational (animal) or Degradation of target RNA (plants) ? Regulation of cell proliferation, differentiation, apoptosis, carcinogenesis and viral infection ? Unknown function of newly identified animal miRNA The model for biogenesis and post-transcriptional suppression of miRNA and siRNA Purpose ? Computational target gene prediction ? Identification of microRNA function ? Expression pro