(精编)Clinical Trials of Anti-Hypertensive Medication for MCI ...教学课件.pptVIP

But…..both risk factors and dementia needs to be detected….. Many people have hypertension without knowing it Many people have dementia or cognitive impairment which is not detected The latter may have implications for adherence to medications for physical disorders Lille, France 12-14 Septembre 2011 Vas-Cog2011 Declining blood pressure before dementia onset A 15-year follow-up of blood pressure and dementia Skoog et al. Lancet 1996 SAMPLES SHEP 160-219/90 MRC 160-209/115 Syst-Eur 160-219/95 No dementia PROGRESS Prior stroke or TIA Mean age 64 SCOPE 160-179/90-99 MMSE 24-30 No dementia HY