(精编)Pediatric Acute Kidney Injury (AKI)教学课件.pptVIP

Management: Intravascular Volume Diuretics Augmentation of Loop with addition of Thiazide Augment loop diuretics by delivering more Cl to the distal tubule by blunting Na reaborption Fiser et al, Kid Int 1994 46:482 IV thiazide vs Control to augment loop in 10 adults with AKI Thiazide addition resulted in sig improvement in UOP 5mg/kg/dose q6 Diuril followed by Lasix IV q6 or Lasix gtt Management: Intravascular Volume Albumin good or bad? Finfer et al, NEJM 2004 350:2247 ~7000 adults with hypovolemia randomized to NS or 4% albumin No difference in AKI or need for dialysis BUT NS group rece