哮喘吸入糖皮质激素治疗的安全性(128p)教学教程.ppt

理想的吸入激素应具备的特点 吸入型糖皮质激素与全身皮质激素由于分子结构的显著差别导致其给药方式，代谢途径的显著不同。 哮喘症状是“冰山的一角” 平时我们所看到患者哮喘症状，只是哮喘疾病的这座冰山露出水面的那一小部分。水面下的部分才是哮喘真正的病因，更大更危险。所以，哮喘治疗不能仅对症，更要对因。 It may be helpful to look at the results of the GOAL study in light of observations by Woolcock, who looked at the proportional improvement over time of various aspects of asthma. In phase I of GOAL, we expected marked reduction in some of the more sensitive endpoints of asthma, night-time symptoms and modification of lung function (measured with either FEV1 or peak expiratory flow). However, we still needed to consider the treatment effects du