病理生理学第十章呼吸功能不全孔小燕.ppt

INCITING FACTORS Shock Aspiration of gastric contents Trauma Infections Inhalation of toxic gases and fumes Drugs and poisons Miscellaneous（多种多样的） STAGES Acute, exudative（渗出） phase rapid onset of respiratory failure after trigger diffuse alveolar（肺泡） damage with inflammatory cell infiltration（浸润） Hyaline（透明） membrane formation capillary injury protein-rich edema fluid in alveoli disruption of alveolar epithelium NORMAL ALVEOLUS Type I cell Endothelial Cell RBC’s Capillary Alveolar macrophage Type II cell ACUTE PHASE OF ARDS Type I cell Endothelial Cell RBC’s Capillary Alveolar macrophag