黏膜医学教学（中山大学）1-粘膜总论，变态反应性疾病.pptVIP

DIAGONOSIS Medical history. Allergen Clinical manifestation. Acute inflammation . Remove suspicious allergen. Lesions would improve. Allergic stomatitis THERAPY Removing of suspicious allergen or avoidance of contactants is the primary mode of therapy Corticosteroid and antihistamine treatment Supportive therapy.Nutritional supplement. Therapies according to clinical signs and symptoms. Topical and systemic medicaments. Allergic stomatitis Angioneurotic edema Recurring periods of noninflammatory swelling involving the skin, intestinal organs, brain and mucous membranes In severe cases, respiratory swelling can result in compromised breathing Type I hypersensitivity Allergen: uncertain, probably foods, drugs, mental / physical conditions Clinical Features Joint pain Purpura Fever Skin swelling Mucous membrane swelling Brain swelling Visceral swelling Abdominal pain Voice box swelling various sources for Angioneurotic Edema includes the 9 symptoms listed below: THERAPY Removing of suspicious allergen is the primary mode of therapy Corticosteroid , adrenaline, antihistamine treatment Supportive therapy.Nutritional supplement. Therapies according to clinical signs and symptoms. Topical and systemic medicaments. Angioneurotic edema Erythema Multiforme A mucocutaneous condition of unknown cause, possibly mediated by deposition of immune complex (mostly IgM) in the superficial microvasculature of the skin and oral mucosa Acute eruption, self-limiting and recurrent Clinical Presentations Symptoms - prodromal stage: tired, fever, headache, sore throat, sneeze, cough Signs -lesions usually appear symmetrically - Oral lesion: extensive erosion, exudation, pseudomembrane, crust (especially on lips) - Skin lesion: Central sore surrounded by pale red rings, also called a target, iris, or bulls-eye” Clinical Presentations Other damage - “Stevens–Johnson syndrome” (erythema multiforme major) - A serious systemic disorder with the potential for severe morbi