Immunosenescence of microglia and macrophages impact on the ageing central nervous system（小胶质细胞和巨噬细胞的免疫衰老对中枢神经系统衰老的影响）.pdfVIP

doi:10.1093/brain/awv395 BRAIN 2016: 139; 653–661 | 653 UPDATE Immunosenescence of microglia and macrophages: impact on the ageing central nervous system Khalil S. Rawji,1 Manoj K. Mishra,1 Nathan J. Michaels,1 Serge Rivest,2 Peter K. Stys1 and V. Wee Yong 1 Ageing of the central nervous system results in a loss of both grey and white matter, leading to cognitive decline. Additional injury to both the grey and white matter is documented i