江西农业工程职业学院农技推广人员.pptVIP

John McGrathSukanta SahaJoy WelhamDavid Chant Aims To systematically identify and collate studies of the prevalence of schizophrenia To summarize variation in time, place and person by examining the distribution of these estimates of prevalence To explore factors which may influence prevalence estimates Outline Research questions Methods Systematic reviews Key results Caveats and Conclusions The prevalence of schizophrenia:Hypotheses Sex difference Males females Migrant status Migrants native born Urbanicity Urban born rural born Types of prevalence studies ‘Core studies’ Sentinel surveys Register based studies Migrant studies Cohort studies Other special groups Methods: systematic review Electronic data search Medline, PsychoInfo, Embase, LILAC 1965-2001 inclusive (schizo* OR psycho*) AND incidence OR prevalence) also Review article bibliography Wrote to authors Screen abstract and reviewed papers to cull irrelevant citations Rate items and discrete data Non-overlapping Sex Male, Female Overlapping Age eg all ages or age 15-54 Diagnosis eg Catego S+ or Catego SPO + clinical Diagnostic categories eg DSMIV Schizophrenia or Schizophrenia + Delusional disorder Site overlap eg Denmark or Copenhagen Epoch overlap eg 1990-92 or 1989-91 Data analysis: example cumulative distribution Results Electronic search = 834 potential papers Manual checking = 249 potential papers Letters from 52 authors, who provided an additional 41 references Of potentially relevant papers, 74% were identified from electronic sources Results (2) Rates based on 176,056 potentially overlapping incident cases After review 158 were included from 32 countries Types of studies Core studies = 100 Migrant studies = 24 Cohort studies = 23 Other special groups = 14 Migrant status Urban-rural differences Cohort studies Australia (n=2) Denmark (n=3) Finland (n=5) Israel (n=2) Italy (n=