中大生物化学试题(2005秋季.docVIP

生物化学I（2005年秋季学期, B卷） 专业(班级)： 姓名： 学号： 阅卷教师： 题号 一 二 三 四 五 六 合计 分数 《中山大学授予学士学位工作细则》第六条：“考试作弊不授予学士学位”。 一、选择唯一正确答案（每小题2分，共30分） 1. When the pH is 2 units below the pKa of a specific group, the ratio of protonated to unprotonated species in the solution is 10:1 in favor of the protonated form. 100:1 in favor of the unprotonated form. 1000:1 in favor of the unprotonated form. 100:1 in favor of the protonated form. Equal amount of the protonated and unprotonated forms. 2. The titration curve shown below is most characteristic of the amino acid Tyrosine Valine Glutamic acid Lysine Glycine 3. Which one of the local anesthetics shown below will exist to a greater extent in their protonated form at physiological pH (pH 7.4)? Novacaine Lignocaine both Novacaine and Lignocaine will be fully deprotonated both Novacaine and Lignocaine will be fully protonated Novacaine and Lignocaine will be protonated to the same extent 4. In a mixture of the five proteins listed below, which should elute second in size-exclusion (gel filtration) chromatography? cytochrome c, Mr = 13,000 immunoglobulin G, Mr = 145,000 ribonuclease A, Mr = 13,700 RNA polymerase, Mr = 450,000 serum albumin, Mr = 68,500 5. Which of the following best represents the backbone arrangement of two peptide bonds? C(-N-C(-C-C(-N-C(-C C(-N-C-C-N-C( C-N-C(-C(-C-N C(-C-N-C(-C-N C(-C(-C-N-C(-C(-C 6．Which one of the following statements regarding the carbohydrate structures shown below is FALSE? Carbohydrate I has an? ?-1,4 linkage, whereas carbohydrate II has a ?-1,4 linkage. Carbohydrate I and carbohydrate II are both characterized as having their free anomeric hydroxyls in the? ???conformation. Carbohydrate I and Carbohydrate II are both of the D-configuration. Carbohydrate I and Carbohydrate II are reducing carbohydrates. None of the above is FALSE. 7．The glucose storage polymer, glycogen, which is shown below in schema