心衰中的炎症-课件，幻灯， (英文）.pptVIP

* Simvastatin reduces TNF-α expression in myocardium Zhang JY, Cheng X, Liao YH, et al. Cardiovasc Drug Ther. 2005;19:13-21 MI MI-S Non MI area MI area * *P0.01 vs Sham # P0.01 vs MI-C Simvastatin modulate cytokines protein expression after AMI Zhang JY, Cheng X, Liao YH, et al. Cardiovasc Drug Ther. 2005; 19(1): 13-21 * Heart function improved in AMI rats after simvastatin treatment Groups n LVEDd (mm) EF (%) FS (%) Sham 10 4.5±0.3 85.2±3.7 51.6±3.1 MI-C 12 7.5±0.4* 41.4±4.3* 20.5±2.5* MI-S 12 5.9±0.3# 51.8±4.3# 25.4±2.7# Sham MI-C MI-S ED ES Compared with sham group, *p0.01 Compared wit