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新SAT官方指南阅读第三篇全解析
This passage is adapted from J.D. Watson and F.H. C.Crick, “Genetical Implications of the Structure of
C
DeoxyribonucleicAcid.” ○1953 by Nature Publishing Group. Watson and Crick deduced the structure of DNA
usingevidencefrom RosalindFranklinand R.G.Gosling’sX-raycrystallographydiagramsof DNAandfrom Erwin
Chargaff’sdataonthebasecompositionofDNA.
Thechemicalformulaofdeoxyribonucleicacid(DNA)isnowwellestablishedthemoleculeis
averylongchain,thebackboneofwhichconsistsofaregularalternationofsugarandphosphate
groups.Toeachsugarisattachedanitrogenousbase,whichcanbeoffourdifferenttypes.Twoof
the possible bases-adenine and guanine-are purines, and the other two-thymine and
5 cytosine-are pyrimidines.Sofar as isknown,the sequence of basesalongthe chain isirregular.
Themonomerunit,consistingofphosphate,sugarandbase,isknownasanucleotide.
Thefirstfeatureofourstructurewhich isof biologicalinterestisthat itconsists notofone
chain, but of two. These two chains are both coiled around a common fiber axis. It has often
beenassumedthat sincethere was only onechain inthe structural unit. However,the density,
10 takenwiththeX-rayevidence,suggestsverystronglythattherearetwo.
The other biologically important feature is the manner in which the two chains are held
together.This isdone byhydrogen bonds betweenthe bases.The basesarejoined together in
pairs,asingle basefrom onechainbeinghydrogen-bondedtoasingle basefromthe other.The
1
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