CH04 analysis of variance Medical Statistics医学统计学 演示教学.pptVIP

Chapter 4;Section 1 the basic idea and condition of application; Objective: deduce and compare several (or two ) population means . Method: analysis of Variance (ANOVA), ie F test for comparing several sample means . Basic idea : according to the type of design, the sum of squares of deviation from means (SS) and degree of freedom (df) were divided into two or several sections . Except the chance error, the variation of every section can be explained by a certain or some factors. ;Condition of Application : population : normal distribution and homogeneity of variance. Sample: independent and random Types of design : The ANOVA of completely random design; The ANOVA of randomized block design; The ANOVA of Latin square design; The ANOVA of cross-over design ;;The basic idea of ANOVA of completely random design; 2. between- group variation: the sum of squares of deviations from mean between groups means and grand mean show the effects of treatment and random error, the formula : ;3.Within-group Variation : differences among values within each group .The formula as follows: ;the relation of three variation; ;Test statistic：;Section 2; All of objects were randomly distributed to g groups (levels), and every group give the different treatment. The effects of treatment will be deduced by comparing the groups means after experimentation. ; Example 4-1 A doctor want to explore the clinic effect of a new medicine for reducing blood fat, and selects 120 patients according to the same standard. All of patients were divide into 4 groups by the completely random design. How should he divide the groups? ;The methods of dividing groups of completely random design ;3.edit serial number: edit serial number according to the number from small to large (the same number according to early or late order) (table 4-2,column 3) 4.define in advance: the serial numbers from 1-30 were defined the A group; 31-60 were the B group; 61-90 were the C group;