垂体后叶素与催产素用于腹腔镜下输卵管间质部妊娠术中止血效果比较.docVIP

垂体后叶素与催产素用于腹腔镜下输卵管间质部妊娠术中止血效果比较 作者：王爱丽,黄守国,陈彦 单位：中南大学湘雅海口医院，海南 海口 570208 【摘要】目的：探讨垂体后叶素与催产素在腹腔镜下输卵管间质部妊娠术中的止血效果。方法：诊断为输卵管间质部妊娠患者40例，垂体后叶素用于腹腔镜下输卵管间质部妊娠术20例(A组)，催产素用于腹腔镜下输卵管间质部妊娠术20例(B组)，观察出血量、手术时间。结果：A组平均出血量为18.78mL，B组为70.92mL;A组平均手术时间为30.07min，B组为62.82min，两组比较差异均有统计学意义(P均lt;0.01)。手术病理均为输卵管间质部妊娠，血beta;HCG两组均4周内降至正常。无1例并发症发生。结论：垂体后叶素用于腹腔镜下输卵管间质部妊娠术可明显减少出血量，缩短手术时间，是一种安全、有效的止血方法。 【关键词】 输卵管间质部妊娠;腹腔镜;垂体后叶素;催产素;止血 　Comparison of the hemostasis effect of pituitrin and oxytocin in the resection of interstitial pregnancy under laparoscopy 　　WANG Aili， HUANG Shouguo， CHEN Yan 　　(Xiangya Hospital in Haikou Affiliated to Central South University, Haikou 570208, China) 　　[ABSTRACT] Objective: To discuss the hemostasis effect of pituitrin and oxytocin in the resection of interstitial pregnancy under laparoscopy. Methods: Out of 40 cases with confirmed interstitial pregnancy, there were 20 cases treated by pituitrin(group A), and 20 cases by oxytocin(group B).The operative time，the bleeding volume during the operation were observed. Results: The bleeding volume during operation was 18.78 mL in group A, and 70.92 mL in group B. The operative time was 30.07 min in group A, and 62.82 min in group B. There was significant differences in these indexes between two groups(Plt;0.01). Pathological test confirmed interstitial pregnancy. The level of beta;HCG in blood declined into normal in 4 weeks, and no complication occurred. Conclusions: Pituitrin can obviously decrease the bleeding volume, shorten the operative time in the resection of interstitial pregnancy under laparoscopy.Itrsquo;s safe and effective. 　　[KEY WORDS] Interstitial pregnancy; Laparoscopy; Pituitrin;Oxytocin;Hemostasis 　　几乎所有异位妊娠均可以通过腹腔镜进行诊断和治疗，但对输卵管间质部的妊娠者由于病灶大，局部血供丰富，术中出血多，难于控制而中转开腹手术，以至于行全子宫切除术的不在少数。近年来随着本院腹腔镜技术不断进步，采用术中病灶基底部注射垂体后叶素(0.3U/mL)20例，与术中病灶基底部注射催产素(1U/mL) 20例观察比较,垂体后叶素在治疗输卵管间质部妊娠中减少术中出血量，缩短手术时间方面取得了满意的效果，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　2005年1月～2009年12月我院收治诊断为输卵管间质部妊娠共40例，年龄18～36岁，平均年龄(25.00plusmn;3.25)岁，