垂体后叶素防治剖宫产病人术中出血的作用.docVIP

垂体后叶素防治剖宫产病人术中出血的作用 作者：郭豪 单位：梧州市工人医院妇产科 【摘要】 目的探讨垂体后叶素联合缩宫素防治剖宫产病人术中出血的作用。方法 在我院住院剖宫产分娩的产妇中，有术中出血倾向、无血压升高的产妇160例，随机分为实验组和对照组。实验组80例胎儿娩出后即子宫体肌注缩宫素20 U及子宫下段肌注垂体后叶素6 U,对照组80例胎儿娩出后即子宫体肌注缩宫素20 U，比较两组术中出血量及术毕阴道积血量。结果 实验组术中出血量及术毕阴道积血量较对照组明显减少，差异有显著性（t=10.81，tprime;=4.38，Plt;0.01）。结论 垂体后叶素联合缩宫素对防治剖宫产病人术中大出血有明显作用。 【关键词】 垂体激素类　后叶　剖宫产术　产后出血 　　PREVENTIVE EFFECT OF PITUITRIN ON INTRAOPERATIVE HEMORRHAGE IN CESAREAN DELIVERY 　　GUO HAO 　　(Department of Gynecology and Obstetrics, Wuzhou Workersrsquo; Hospital, Wuzhou 543001, China) ; 　　［ABSTRACT］ Objective To investigate the effects of combined usage of pituitrin and oxytocin in the prevention of hemorrhage during cesarean section. Methods This study consisted of 160 puerperas, with bleeding tendency, but without hypertension, who were hospitalised for cesarean section evenly randomized to experiment group and control group. To the experiment,i.m. of 20 U of oxytocin was given to the uterine body and 6 U of pituitrin to the lower uterine segment, postoperatively; to the control, 20 U of oxytocin alone was given. The intraoperative hemorrhage and hematocolpos at the end of the surgery were compared between the two groups. Results Both the volume of hemorrhage during operation and hematocolpos at the end of the surgery of the experiment were much less than the control (t=10.81,tprime;=4.38,P＜0.01). Conclusion Combined usage of pituitrin and oxytocin is effective in the prevention and treatment of massive hemorrhage during cesarean delivery. 　　［KEY WORDS］ pituitary hormones, posterior; cesarean section; postpartum hemorrhage 　　产后出血是产科常见的严重并发症之一，为产妇死亡的首要原因。引起产后出血的主要原因是子宫收缩乏力，占产后出血总数的70%～80%，而剖宫产分娩产后出血率为阴道分娩的4～5倍，术中往往发现子宫下段收缩欠佳是导致剖宫产出血量增加的主要原因，严重地胁着母子生命安全[12]。因而加强术中子宫下段收缩是减少产后大出血发生率的重点，我院采用垂体后叶素配伍缩宫素预防及治疗剖宫产术中大出血取得良好效果，现报告如下。 　　1 资料与方法 　　1.1 一般资料 　　2007月6月mdash;2008年6月，选择在我院行剖宫产术的有术中出血倾向、无血压升高的产妇160例，随机分为实验组和对照组各80例，两组病人年龄、孕周、产次、新生儿体质量及妊娠合并症等条件具有可比性。两组剖宫产指征比较差异无显著性(Pgt;0.05),见表1。表1 两组剖宫产指征比较（例）组别n骨盆（略） 　　1.2 方法 　　1.2.1 给药方法 　　两组均采用硬膜